On the Cancer Frontier: One Man, One Disease, and a Medical Revolution

James Sterngold


In 1950, a analysis of melanoma was once all yet a demise sentence. Mortality premiums basically received worse, and as overdue as 1986, a piece of writing in the New England magazine of Medicine lamented: “We are wasting the struggle opposed to cancer.” melanoma is one among humankind’s oldest and such a lot chronic enemies; it's been referred to as the existential disease.

But we're now coming into a brand new, and extra confident, section during this lengthy crusade. whereas melanoma has now not been cured—and a medication could elude us for a very long time yet—there has been a revolution in our knowing of its nature. Years of exceptional technology have published how this individualistic ailment seizes keep an eye on of the principles of life—our genes—and produces guerrilla cells that may assault and elude remedies. Armed with these insights, scientists were constructing more desirable guns and generating greater results for sufferers. Paul A. Marks, MD, has been a pacesetter in those efforts to eventually keep watch over this devastating disease.

Marks helped determine the method for the “war on melanoma” in 1971 as a researcher and member of President Nixon’s melanoma panel. because the president and leader government officer for nineteen years on the world’s pre-eminent melanoma clinic, the Memorial Sloan-Kettering melanoma heart, he was once instrumental in finishing the years of futility. He additionally built greater cures that promise a brand new period of melanoma containment. a few cancers, like youth leukemia and non-Hodgkin’s lymphoma, that have been as soon as lethal stipulations, are actually survivable—even curable. New steps in prevention and early prognosis are giving sufferers much more wish. On the melanoma Frontier is Marks’ account of the transformation in our knowing of melanoma and why there's growing to be optimism in our skill to forestall it.

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